Our paper showing how virus capsids “surf” on microtubule-like PhuZ filaments toward a nucleus they build when infecting bacteria is out. Bacterial Cell Biology at it’s weirdest!
Kanika’s work on bacterial engulment is posted in the bioRxiv.
Elizabeth was honored to serve as co-guest editor for Klaus Schulten’s Memorial issue, published in The Journal of Physical Chemistry B.
In collaboration with the Poglianos and Agard labs, we unveiled how very large viruses affect the cellular machinery of bacteria during infection. The most exciting finding: segregation of the (viral) genetic material inside a shell forming a nucleus-like compartment that separates transcription and translation! We used cryo-FIB milling and cryo-electron tomography to reveal the molecular details of this phenomenon. Read our paper and watch a movie.
Our paper with the Baumeister lab revealing the molecular sociology at the HeLa cell nuclear periphery was published in Science.
Our paper describing the architecture of the RNA polymerase II-Mediator core transcription initiation complex with the Cramer lab was published in Nature.
Our paper with the Baumeister lab describing the molecular architecture of chloroplasts using r in situ cryo-electron tomography was published in eLife.