The Villa Lab develops tools to observe macromolecular complexes in their natural environment, the cell. Our ultimate goal is to unveil the structural dynamics of these complexes while they go about their everyday life. We combine cell biology and electron microscopy to generate data, and we use image processing and physical modeling to understand these data.
Our paper showing how virus capsids “surf” on microtubule-like PhuZ filaments toward a nucleus they build when infecting bacteria is out. Bacterial Cell Biology at it’s weirdest!
Digvijay is named Damon Runyon Fellow, an honor awarded to only eighteen “outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior (?) investigators across the country.” Congratulations Digvijay!
Kanika’s work on bacterial engulment is posted in the bioRxiv.